Sunday, January 11, 2015

SysBio15 Asgn_4A_Class_04_Article_04_2015_01_15

C. difficile and the Microbiome: Read Article 04  F. Bäckhed, R.E. Ley, J.L. Sonnenburg, D.A. Peterson and J.I. Gordon "Host-Bacterial Mutualism in the Human Intestine," Science, 307 (5717): 1915-1920 (2005).

Post a PCRC on the Blog.

SysBio15 Asgn_4B_Class_04_Article_05_2015_01_15

C. difficile and the Microbiome: Scan Article 05  R.E. Ley, D.A. Peterson, and J.I. Gordon, "Ecological and Evolutionary Forces Shaping Microbial Diversity in the Human Intestine," Cell 124, 837–848 (2006).
Focus on Figure 1 and Table 1. Post a PCRC on the blog.

SysBio15 Asgn_4C_Class_04_Article_06_2015_01_15

C. difficile and the Microbiome: Read Article 06  M. Rupnik, M.H. Wilcox, and D.N. Gerding, "Clostridium difficile infection: new developments in epidemiology
and pathogenesis," Nature Revs Microbiol, 7: 526-536 (2009).

Post a PCRC on the Blog. Ultimately, the class will be focusing how to describe the mechanism of action of TCDA and TCDB, not the infection itself.