Control: Read Article 03 P. R. LeDuc, W. C. Messner, and J. P. Wikswo.
How do control-based approaches enter into biology?
Annu.Rev.Biomed.Engr. 13:369-396, 2011.
This article addresses a problem central to much of existing biology,
systems biology, and organs on a chip -- much of the work to date has
been done in an open-loop manner, and hence does not adequately probe
the system dynamics. Post a PCRC on the Blog.
The Systems Biology of COVID-19 and the SARS-CoV-2 virus. The class will build a foundation that includes the emergence of complexity, simple biological subsystems, their reductionist and equivalent toy and organ-chip models, and the measurements required to specify model architecture and parameters. Applications to biology, physiology, medicine, chemical and biological defense, pharmacology, drug discovery, and toxicology. UGrad: PHYS 240 01 and BME 290B; Grad: PHYS 326 and BME 395C.
