The Systems Biology of COVID-19 and the SARS-CoV-2 virus. The class will build a foundation that includes the emergence of complexity, simple biological subsystems, their reductionist and equivalent toy and organ-chip models, and the measurements required to specify model architecture and parameters. Applications to biology, physiology, medicine, chemical and biological defense, pharmacology, drug discovery, and toxicology. UGrad: PHYS 240 01 and BME 290B; Grad: PHYS 326 and BME 395C.
Tuesday, September 6, 2016
SysBio16 Asgn_6A_Class_06_Article_06_2016_09_13
Cisplatin Mech of
Action: Read Article 06 Norris, et al.,Global cell response captured in 30
days yields comprehensive drug mechanism, submitted.. Post a PCRC on the
Blog.
SysBio16 Asgn_5B_Class_05_Article_05_2016_09_08
Circadian modulation;
Eli Lilly guests: Read Article 05 F. Gachon and D. Firsov. The role of
circadian timing system on drug metabolism and detoxification. Expert
Opin.Drug Metab.Toxicol. 7 (2):147-158, 2011.. Post a PCRC on the Blog.
SysBio16 Asgn_5A_Class_05_Article_04_2016_09_08
Circadian modulation; Eli Lilly guests: Read Article
04 Graham R. McGinnis and Martin E. Young. Circadian regulation of
metabolic homeostasis: causes and consequences. Nat.Sci.Sleep 8:163-180,
2016.. Post a PCRC on the Blog.
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