The Systems Biology of COVID-19 and the SARS-CoV-2 virus. The class will build a foundation that includes the emergence of complexity, simple biological subsystems, their reductionist and equivalent toy and organ-chip models, and the measurements required to specify model architecture and parameters. Applications to biology, physiology, medicine, chemical and biological defense, pharmacology, drug discovery, and toxicology. UGrad: PHYS 240 01 and BME 290B; Grad: PHYS 326 and BME 395C.
Epithelial-to-Mesenchymal Transition
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ReplyDeletereprogramming muller glia to generate photoreceptors in mammals
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ReplyDeleteReprogramming iPSCs to GABAergic and glutamatergic neurons, as well as the related pathway of iPSCs to region-specific astrocytes
ReplyDeleteEffect of gene regulatory networks on proteins (tau, for example) implicated in alzheimer's disease.
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ReplyDeleteDriving stem cell differentiation towards a beta cell fate
ReplyDeleteDriving iPSC to DA neuron
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