The Systems Biology of COVID-19 and the SARS-CoV-2 virus. The class will build a foundation that includes the emergence of complexity, simple biological subsystems, their reductionist and equivalent toy and organ-chip models, and the measurements required to specify model architecture and parameters. Applications to biology, physiology, medicine, chemical and biological defense, pharmacology, drug discovery, and toxicology. UGrad: PHYS 240 01 and BME 290B; Grad: PHYS 326 and BME 395C.
Will Matloff
ReplyDelete4D/The energetic cost of moving about.
0. Knew: The main mediums for transportation in biology are water, land, and air.
1. Learned: The relative energy cost associated with moving decreases with size.
2. Pressing?: Is the sloth an exception to these trends?
3. Presentation: Gliding.
4. Thoughts: This paper really highlights how physical properties of the environment influence life.
Brian Evans
ReplyDelete4D/The Energetic Cost of Moving About
0. Knew: Bicycling is easier than walking.
1. Learned: That when a human is running half of the energy produced is from energy stored in elastic structures.
2. Pressing?: Have people looked at this with unicellular organisms? Can we derive biomimetic cellular motors from the evolution of cellular locomotion in these organisms?
3. Presentation: The Energy Cost of Cellular Locomotion
4. Thoughts: I think this paper provides a lot of insight into how humans have engineered locomotion by mimicking the biomechanics of other flying and swimming animals.
http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0029797
ReplyDeleteErica Curtis
ReplyDelete4D/The Energetic Cost of Moving About
0. Knew: The dynamics of different forms of transport/locomotion have an effect on the energy cost of that movement.
1. Learned: Stretching of muscles decreases the efficiency of that muscle.
2. Pressing ?: Why is swimming still more efficient than running for man? Both forms of exercise involve stretching of muscles. People obviously do not have swimbladders and therefore have to overcome the vertical components working on the center of mass. Can buoyancy account for this difference?
3. Presentation: Treading Water and Other Various Forms of Swimming
4. Thoughts: I thought that the section on how to improve the efficiency of different locomotion was interesting and enjoyed how the paper even connected these concepts to different methods of powering cars.
Lucas Hofmeister
ReplyDelete4D/Energetic Cost of Moving About
0. Knew: cycling is efficient
1. Learned: Local minima for power input and cost of transport dont occur at the same flight speed
2. Pressing?: What about animals that hop?
3. Presentation: Energy expenditure in animals that hop
4. Thoughts: It is interesting that animals which run but have very different gaits are grouped on the same line. Along with that and my obsession with kangaroos/hopping, a bunch of mice hop around, i wonder if there should be a separate category there because it seems like mice and kangaroos dont fit any of the lines. also, a bunch of birds hop when they "run" and they have the same backwards knee structure
Ayeeshik Kole
ReplyDelete4D/The Energetic Cost of Moving About
0. Knew: Different forms of transportation have different energy costs.
1. Learned: Biking is a very efficient form of transportation.
2. Pressing ?: What sort of biomimetic robots are being created to exploit what we've learned from nature?
3. Presentation: Advances in bicycle technology
4. Thoughts: I thought it was a good discussion of different transportation mechanisms and their associated costs. It was interesting how relevant it remains 37 years later.
Zach Eagleton
ReplyDelete4D/Energetic Cost of Moving About
0 Knew: bicycling is efficient
1 Learned: How different modes of locomotion rank in energy efficiency
2 Pressing ?: How do different types of cells rank in efficiency?
3 Presentation: muscle efficiency
4 thoughts : I though it was very interesting article and am surprised that swimming is more effiecient than flying
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